Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Taraxasterol regulates p53 transcriptional activity to inhibit pancreatic cancer by inducing MDM2 ubiquitination degradation

7 Dec 2024

Abstract excerpt

No abstract is available from the source.

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Natural Compounds in Disease Treatment
Share to Natural product bioactivities and synthesis

Source

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Identifiers

PMID: 39671783
DOI: 10.1016/j.phymed.2024.156298

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Taraxasterol regulates p53 transcriptional activity to inhibit pancreatic cancer by inducing MDM2 ubiquitination degradationPMID 39671783Read ↗

Apigenin as an effective anticancer natural product: Spotlight on TRAIL, WNT/β‐catenin, JAK‐STAT pathways, and microRNAsSemantic proximity Read ↗

Targeting ubiquitin-proteasome pathway by natural, in particular polyphenols, anticancer agents: Lessons learned from clinical trialsSemantic proximity Read ↗

MED12 Controls the Response to Multiple Cancer Drugs through Regulation of TGF-β Receptor SignalingSemantic proximity Read ↗

Flavokawain A induces deNEDDylation and Skp2 degradation leading to inhibition of tumorigenesis and cancer progression in the TRAMP transgenic mouse model.Semantic proximity Read ↗

Bufalin-Mediated Regulation of Cell Signaling Pathways in Different Cancers: Spotlight on JAK/STAT, Wnt/β-Catenin, mTOR, TRAIL/TRAIL-R, and Non-Coding RNAsSemantic proximity Read ↗

Enhanced Mdm2 activity inhibits pRB function via ubiquitin‐dependent degradationSemantic proximity Read ↗

Itch inhibits IL-17-mediated colon inflammation and tumorigenesis by ROR-γt ubiquitinationSemantic proximity Read ↗

Parthenolide promotes the ubiquitination of MDM2 and activates p53 cellular functionsSemantic proximity Read ↗

Cinobufagin restrains the growth and triggers DNA damage of human hepatocellular carcinoma cells via proteasome-dependent degradation of thymidylate synthaseSemantic proximity Read ↗

[6]-Paradol Suppresses Proliferation and Metastases of Pancreatic Cancer by Decreasing EGFR and Inactivating PI3K/AKT SignalingSemantic proximity Read ↗

ITCH nuclear translocation and H1.2 polyubiquitination negatively regulate the DNA damage responseSemantic proximity Read ↗

Promotion of ubiquitination-dependent survivin destruction contributes to xanthohumol-mediated tumor suppression and overcomes radioresistance in human oral squamous cell carcinomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.