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Article

A let-7 microRNA polymorphism in the KRAS 3'-UTR is prognostic in oropharyngeal cancer.

Cancer epidemiology - 1 Oct 2014

De Ruyck Kim, Duprez Fréderic, Ferdinande Liesbeth, Mbah Chamberlain, Rios-Velazquez Emmanuel, Hoebers Frank, Praet Marleen, Deron Philippe, Bonte Katrien, Speel Ernst-Jan, Libbrecht Louis, De Neve Wilfried, Lambin Philippe, Thierens Hubert

Abstract excerpt

INTRODUCTION: This study aimed to investigate the effect of genetic polymorphisms in miRNA sequences, miRNA target genes and miRNA processing genes as additional biomarkers to HPV for prognosis in oropharyngeal squamous cell carcinoma (OPSCC) patients. Secondarily, the prevalence of HPV-associated OPSCC in a European cohort was mapped. METHODS: OPSCC patients (n=122) were genotyped for ten genetic polymorphisms...

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Identifiers

PMID: 25127693
DOI: 10.1016/j.canep.2014.07.008

Genes

KRAS
XPO5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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