Article
The value of Mentzer index in the diagnosis of children thalassemia minor.
Hematology (Amsterdam, Netherlands) - 1 Dec 2024
Wu Tao, Ren Zhenmin, Feng Yandie, Li Defa, Chen Yunsheng
Abstract excerpt
OBJECTIVE: To explore the effect of the Mentzer Index (MI) in screening for children thalassemia (TT) minor. METHODS: We determined the MI cutoff value of diagnosing TT minor in children by utilizing a receiver operating characteristic (ROC) curve. Samples with MI values below this threshold, and no detectable gene mutations or IDA were further analyzed using Sanger sequencing or specific primer GAP-PCR. RESULTS:...
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