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LYRM2 Promotes the Growth and Metastasis of Hepatocellular Carcinoma via Enhancing HIF ‐1α‐Dependent Glucose Metabolic Reprogramming

1 Dec 2024

Abstract excerpt

Hepatocellular carcinoma (HCC) is a foetal malignancy with dismal overall survival. The molecular mechanism underlying the progression of HCC remain largely unknown. LYR motif containing 2 (LYRM2) has been identified as an oncogene in colorectal cancer; however, its expression, functions and molecular mechanism in the context of HCC has not been investigated. Data derived from The Cancer Gemome Atlas, along with...

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PMID: 39661026
DOI: 10.1111/jcmm.70241

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