Article
A novel molecular classification system based on the molecular feature score identifies patients sensitive to immune therapy and target therapy.
Frontiers in immunology - 1 Jan 2024
Li Yang, Ding Yinan, Wang Jinghao, Wu Xiaoxia, Zhang Dinghu, Zhou Han, Zhang Pengfei, Shao Guoliang
Abstract excerpt
Background: Hepatocellular carcinoma (HCC) is heterogeneous and refractory with multidimensional features. This study aims to investigate its molecular classifications based on multidimensional molecular features scores (FSs) and support classification-guided precision medicine. Methods: Data of bulk RNA sequencing, single nucleotide variation, and single-cell RNA sequencing were collected. Feature scores (FSs)...
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