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Article

Investigating the effects of the ARG258HIS mutation on RAD51C in inherited Fanconi Anemia and cancer disease.

Journal of biomolecular structure & dynamics - 1 Feb 2026

Seifeldin Sara, Saeed Mohd, Alshaghdali Khalid, Yousif Elgeli, Abu Sabaa Amal, Rabie Hatem, Siddiqui Samra, Saeed Amir

Abstract excerpt

Fanconi anemia is a rare chromosomal instability disorder associated with developmental abnormalities, bone marrow failure, and a heightened susceptibility to leukemia and other cancers. It is an autosomal recessive genetic disorder, necessitating both parents to carry the faulty gene. Diagnostic methods include blood tests, chromosome breakage assessments, and genetic testing. While there is no cure, treatments...

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Identifiers

PMID: 39648652
DOI: 10.1080/07391102.2024.2431656

Genes

RAD51C

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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