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Analysis of Methylation of Tumor-suppressive miRNAs and KRAS/TP53 Mutations in Pancreatic Juice.

Anticancer research - 1 Dec 2024

Ohtsubo Koushiro, Miyake Kunio, Sato Shigeki, Sakaguchi Hiroyuki, Fukuda Koji, Kotani Hiroshi, Nishiyama Akihiro, Nanjo Shigeki, Yamashita Kaname, Takeuchi Shinji, Yano Seiji, Kuruma Sawako, Nakahodo Jun, Kikuyama Masataka, Taniguchi Hiroaki

Abstract excerpt

BACKGROUND/AIM: We previously reported the usefulness of detecting aberrant methylation in tumor suppressive microRNAs (miRNAs) in bile and plasma to discriminate pancreaticobiliary cancers from benign pancreaticobiliary diseases. This study analyzed the methylation of miRNAs in pancreatic juice to identify those specific to pancreatic cancer (PC). PATIENTS AND METHODS: Pancreatic juice was collected from 20...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39626942
DOI: 10.21873/anticanres.17353

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