Article
Clonal Hematopoiesis Is Associated With Low CD4 Nadir and Increased Residual HIV Transcriptional Activity in Virally Suppressed Individuals With HIV.
The Journal of infectious diseases - 19 Apr 2022
van der Heijden Wouter A, van Deuren Rosanne C, van de Wijer Lisa, van den Munckhof Inge C L, Steehouwer Marloes, Riksen Niels P, Netea Mihai G, de Mast Quirijn, Vandekerckhove Linos, de Voer Richarda M, van der Ven Andre J, Hoischen Alexander
Abstract excerpt
Clonal hematopoiesis, a common age-related phenomenon marked by expansion of cells with clonal hematopoiesis driver mutations, has been associated with all-cause mortality, cancer, and cardiovascular disease. People with HIV (PWH) are at risk for non-AIDS-related comorbidities such as atherosclerotic cardiovascular disease and cancer. In a cross-sectional cohort study, we compared clonal hematopoiesis prevalence...
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