Article
HIV-1 infection is associated with an earlier occurrence of a phenotype related to frailty.
The journals of gerontology. Series A, Biological sciences and medical sciences - 1 Nov 2007
Desquilbet Loic, Jacobson Lisa P, Fried Linda P, Phair John P, Jamieson Beth D, Holloway Marcy, Margolick Joseph B
Abstract excerpt
BACKGROUND: Older healthy and HIV-infected adults exhibit physiological similarities. Frailty is a clinical syndrome associated with aging that identifies a subset of older adults at high risk of mortality and other outcomes. We investigated whether HIV infection increases the prevalence of a frailty-related phenotype (FRP) that approximates a clinical definition of frailty. METHODS: We first defined the FRP and...
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