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Article

Brucella melitensis omp31 Mutant Is Attenuated and Confers Protection Against Virulent Brucella melitensis Challenge in BALB/c Mice.

Journal of microbiology and biotechnology - 28 Apr 2020

Verdiguel-Fernández L, Oropeza-Navarro R, Ortiz Adolfo, Robles-Pesina M G, Ramírez-Lezama J, Castañeda-Ramírez A, Verdugo-Rodríguez A

Abstract excerpt

For control of brucellosis in small ruminants, attenuated B. melitensis Rev1 is used but it can be virulent for animals and human. Based on these aspects, it is essential to identify potential immunogens to avoid these problems in prevention of brucellosis. The majority of OMPs in the Omp25/31 family have been studied because these proteins are relevant in maintaining the integrity of the outer membrane but their...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 31986561
DOI: 10.4014/jmb.1908.08056
PMCID: PMC9728373

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