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Article

RNA-seq reveals the critical role of CspA in regulating Brucella melitensis metabolism and virulence.

Science China. Life sciences - 1 Apr 2016

Wang Zhen, Liu Wenxiao, Wu Tonglei, Bie Pengfei, Wu Qingmin

Abstract excerpt

Brucella melitensis is a facultative intracellular bacterium that replicates within macrophages. The ability of Brucella to survive and multiply in the hostile environment of host macrophages is essential for its virulence. The cold shock protein CspA plays an important role in the virulence of B. melitensis. To analyze the genes regulated by CspA, the whole transcriptomes of B. melitensis NIΔcspA and its...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26740105
DOI: 10.1007/s11427-015-4981-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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