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Predicting Immunogenic Epitopes Variation of Envelope 2 Gene Among Chikungunya Virus Clonal Lineages by an In Silico Approach.

Viruses - 29 Oct 2024

Cho Sung-Yeon, Lee Dong-Gun, Park Jung Yeon, Kim Won-Bok, Lee Raeseok, Nho Dukhee, Oh Eun-Jee, Lee Hyeyoung, Park Chulmin

Abstract excerpt

Chikungunya virus (CHIKV), responsible for a mosquito-borne viral illness, has rapidly spread worldwide, posing a significant global health threat. In this study, we explored the immunogenic variability of CHIKV envelope 2 (E2), a pivotal component in the anti-CHIKV immune response, using an in silico approach. After extracting the representative sequence types of the CHIKV E2 antigen, we predicted the...

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Identifiers

PMID: 39599804
DOI: 10.3390/v16111689
PMCID: PMC11599094

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