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Article

In Silico Identification of Chikungunya Virus B- and T-Cell Epitopes with High Antigenic Potential for Vaccine Development.

Viruses - 24 Nov 2021

Sánchez-Burgos Gilma G, Montalvo-Marin Nallely M, Díaz-Rosado Edgar R, Pérez-Rueda Ernesto

Abstract excerpt

Reverse vaccinology is an outstanding strategy to identify antigens with high potential for vaccine development. Different parameters of five prediction programs were used to assess their sensitivity and specificity to identify B-cell epitopes of Chikungunya virus (CHIKV) strains reported in the IEDB database. The results, based on the use of 15 to 20 mer epitopes and the polyproteins to which they belong, were...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34960629
DOI: 10.3390/v13122360
PMCID: PMC8706625

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