Article
The genetic basis of uveal melanoma.
Journal francais d'ophtalmologie - 1 Jun 2015
Nielsen M, Dogrusöz M, Bleeker J C, Kroes W G, van Asperen C A, Marinkovic M, Luyten G P M, Jager M J
Abstract excerpt
Uveal melanoma (UM) is the most common intraocular malignancy in adults with an incidence of about 1/100,000 new cases per year in the Western world. Risk factors are having a light skin, blond hair and blue eyes. As some UM patients have a young age at diagnosis or an affected family history for UM or other malignancies, there may be an underlying genetic basis. This review discusses known or suspected risk...
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