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Article

Biochemical Investigation of the Association of Apolipoprotein E Gene Allele Variations with Insulin Resistance and Amyloid-β Aggregation in Cardiovascular Disease.

Clinical and experimental pharmacology & physiology - 1 Jan 2025

Jabeen Komal, Rehman Kanwal, Akash Muhammad Sajid Hamid, Hussain Amjad, Shahid Mudassar, Sadaf Bushra

Abstract excerpt

This article investigates the intricate associations between apolipoprotein E (APOE) gene alleles variation, insulin resistance (IR) and amyloid-β aggregation in cardiovascular disease (CVD) patients. A cohort of 250 patients exhibiting the symptoms of CVD and 50 control subjects participated in this study. After applying the stringent inclusion and exclusion criteria, the diseased group was further stratified...

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Source

Identifiers

PMID: 39582253
DOI: 10.1111/1440-1681.70007

Genes

APOE
TG

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 9 Sept 2026.

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