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Concurrent genotyping of mitochondrial DNA and nuclear DNA in rootless hair shafts and blood samples for enhanced analysis.

Forensic science international. Genetics - 1 Feb 2025

Peng Dan, Wang Nana, Zang Yu, Liu Zhiyong, Liu Zhentang, Geng Jiaojiao, Cong Bin, Sun Hongyu, Wu Riga

Abstract excerpt

Hair is an important type of biological evidence at crime scenes. However, the highly degraded nature of DNA fragments in hair shafts poses challenges for the detection of nuclear DNA (nuDNA) through capillary electrophoresis-based short tandem repeat (STR) genotyping. In this study, an all-in-one multiplex system named MGIEasy Signature Identification Library Prep Kit (MGI Tech, China) was employed to the...

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PMID: 39566343
DOI: 10.1016/j.fsigen.2024.103176

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