Article
Rootless hair as a reliable source of forensic genetic information.
Genome biology - 18 Feb 2026
Kapp Joshua D, Wanket Ciara, Nguyen Remy, Tzadikario Talia, Neadeau Hayley, Shapiro Beth, Sacco Samuel, Schwartz Camille, Valencia Cristina, Harkins Kelly, Green Richard E
Abstract excerpt
The small amount of fragmented DNA present in rootless hair shafts is unsuitable for many assays, including most PCR-based assays. Thus, rootless hair DNA is often overlooked in biomedical and forensic analysis. Here we apply methods for efficient recovery and sequencing of minute quantities of short, fragmented DNA to single human hair shafts. Using this approach, we characterize DNA fragments in hair shafts....
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