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Article

A bidirectional Mendelian randomization study of spleen volume and Crohn disease.

Medicine - 15 Nov 2024

Song Hang-Hang, Zhang Hao-Ran, Hu Xiao-Rong, Jiang Xi-Cheng

Abstract excerpt

In observational studies, there has been an association found between spleen volume and Crohn disease. We conducted a two-way, two-sample Mendelian randomization analysis to determine whether these associations have a causal relationship. Single nucleotide polymorphisms (P < 5 × 10-8) were used as instrumental variables for spleen volume and Crohn disease. Estimates of the genetic associations between spleen...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39560526
DOI: 10.1097/MD.0000000000040515
PMCID: PMC11576015

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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