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Article

Nip the HPV encoded evil in the cancer bud: HPV reshapes TRAILs and signaling landscapes

17 Jun 2013

Abstract excerpt

HPV encoded proteins can elicit ectopic protein-protein interactions that re-wire signaling pathways, in a mode that promotes malignancy. Moreover, accumulating data related to HPV is now providing compelling substantiation of a central role played by HPV in escaping immunosurveillance and impairment of apoptotic response. What emerges is an intricate network of Wnt, TGF, Notch signaling cascades that forms...

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PMID: 23773282
DOI: 10.1186/1475-2867-13-61

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