Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Exposure to particulate matter (PM2.5) weakens corneal defense by downregulating thrombospondin-1 and tight junction proteins

1 Nov 2024

Abstract excerpt

Fine particulate matter (PM 2.5 ) induces ocular surface toxicity through pyroptosis, oxidative stress, autophagy, and inflammatory responses. However, the precise molecular pathways through which PM 2.5 causes corneal damage remain unclear. This study aims to investigate the underlying mechanisms by exposing human corneal epithelial cells (HCECs) to PM 2.5 . After the morphology and chemical composition analysis...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Air Quality and Health Impacts
Share to Barrier Structure and Function Studies
Share to Dietary Effects on Health

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 39536561
DOI: 10.1016/j.ecoenv.2024.117276

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Exposure to particulate matter (PM2.5) weakens corneal defense by downregulating thrombospondin-1 and tight junction proteinsPMID 39536561Read ↗

PM2.5 exposure increase dry eye disease risks through corneal epithelial inflammation and mitochondrial dysfunctionsSemantic proximity Read ↗

Transcriptome-wide profiling discover: PM2.5 aggravates airway dysfunction through epithelial barrier damage regulated by Stanniocalcin 2 in an OVA-induced modelSemantic proximity Read ↗

Particulate Matter and Its Molecular Effects on Skin: Implications for Various Skin DiseasesSemantic proximity Read ↗

Particulate matter 2.5 induces the skin barrier dysfunction and cutaneous inflammation via AhR ‐ and T helper 17 cell‐related genes in human skin tissue as identified via transcriptome analysisSemantic proximity Read ↗

Long-term PM2.5 exposure disrupts corneal epithelial homeostasis by impairing limbal stem/progenitor cells in humans and rat modelsSemantic proximity Read ↗

Particulate matter-induced epigenetic modifications and lung complications.Semantic proximity Read ↗

Disease-specific differences in particulate matter handling drive pathogenic responses in human derived nasal epithelial cellsSemantic proximity Read ↗

Pre-pregnancy exposure to fine particulate matter (PM2.5) increases reactive oxygen species production in oocytes and decrease litter size and weight in miceSemantic proximity Read ↗

Fine particulate matter potentiates Th17-cell pathogenicity in experimental autoimmune uveitis via ferroptosisSemantic proximity Read ↗

Impact of airborne total suspended particles (TSP) and fine particulate matter (PM2.5)‐induced developmental toxicity in zebrafish ( Danio rerio ) embryosSemantic proximity Read ↗

Evaluation of the Effects of Airborne Particulate Matter on Bone Marrow-Mesenchymal Stem Cells (BM-MSCs): Cellular, Molecular and Systems Biological ApproachesSemantic proximity Read ↗

Assessment on the lung injury of mice posed by airborne PM2.5 collected from developing area in China and associated molecular mechanisms: from histopathology to integrated transcriptome analysisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.