Article
Fine particulate matter potentiates Th17-cell pathogenicity in experimental autoimmune uveitis via ferroptosis
3 Sept 2024
Abstract excerpt
The effect of fine particulate matter (PM2.5) on the development of uveitis remains unclear. Therefore, this study was designed to investigate the role of PM2.5 in experimental autoimmune uveitis (EAU) and its potential mechanism. Our results showed that PM2.5 could exacerbate the activity of EAU, as evidenced by severer clinical and pathological changes, correlated with elevated Th17 cells frequency and IL-17A...
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