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Predicting Pancreatic Cancer in New-Onset Diabetes Cohort Using a Novel Model With Integrated Clinical and Genetic Indicators: A Large-Scale Prospective Cohort Study.

Cancer medicine - 1 Nov 2024

Sun Yongji, Hu Chaowen, Hu Sien, Xu Hongxia, Gong Jiali, Wu Yixuan, Fan Yiqun, Lv Changming, Song Tianyu, Lou Jianyao, Zhang Kai, Wu Jian, Li Xiawei, Wu Yulian

Abstract excerpt

INTRODUCTION: Individuals who develop new-onset diabetes have been identified as a high-risk cohort for pancreatic cancer (PC), exhibiting an incidence rate nearly 8 times higher than the general population. Hence, the targeted screening of this specific cohort presents a promising opportunity for early pancreatic cancer detection. We aimed to develop and validate a novel model capable of identifying high-risk...

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PMID: 39526476
DOI: 10.1002/cam4.70388
PMCID: PMC11551786

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