Article
Genetic and Circulating Biomarker Data Improve Risk Prediction for Pancreatic Cancer in the General Population.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 May 2020
Kim Jihye, Yuan Chen, Babic Ana, Bao Ying, Clish Clary B, Pollak Michael N, Amundadottir Laufey T, Klein Alison P, Stolzenberg-Solomon Rachael Z, Pandharipande Pari V, Brais Lauren K, Welch Marisa W, Ng Kimmie, Giovannucci Edward L, Sesso Howard D, Manson JoAnn E, Stampfer Meir J, Fuchs Charles S, Wolpin Brian M, Kraft Peter
Abstract excerpt
BACKGROUND: Pancreatic cancer is the third leading cause of cancer death in the United States, and 80% of patients present with advanced, incurable disease. Risk markers for pancreatic cancer have been characterized, but combined models are not used clinically to identify individuals at high risk for the disease. METHODS: Within a nested case-control study of 500 pancreatic cancer cases diagnosed after blood...
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