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Tert‐butyl hydroperoxide induces trabecular meshwork cells injury through ferroptotic cell death

28 Aug 2024

Abstract excerpt

Trabecular meshwork (TM) tissue has a crucial role in regulating aqueous humor circulation in the eye, thus maintaining normal intraocular pressure (IOP). TM dysfunction causes IOP elevation, which leads to glaucoma. To investigate biological changes in TM tissue in patients with glaucoma, we analyzed the mRNA expression microarray dataset, GSE27276. Gene ontology analysis indicated that redox microenvironment...

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PMID: 39524143
DOI: 10.1002/ccs3.12050

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