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High Glucose-induced transcriptomic changes in human trabecular meshwork cells

25 Apr 2025

Abstract excerpt

Glaucoma is a leading cause of irreversible blindness, often associated with elevated intraocular pressure (IOP) due to trabecular meshwork (TM) dysfunction. Diabetes mellitus (DM) is recognized as a significant risk factor for glaucoma; however, the molecular mechanisms through which hyperglycemia affects TM function remain unclear. This study investigated the impact of high glucose on gene expression in human...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 40278947
DOI: 10.1007/s11033-025-10525-z

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