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Article

Loss of quality of life and increased societal costs in patients with hypertrophic cardiomyopathy: the AFFECT-HCM study.

European heart journal. Quality of care & clinical outcomes - 3 Mar 2025

Schoonvelde Stephan A C, Wiethoff Isabell, Zwetsloot Peter-Paul, Hirsch Alexander, Knackstedt Christian, Germans Tjeerd, Sikking Maurits, Schinkel Arend F L, van Slegtenhorst Marjon A, Verhagen Judith M A, de Boer Rudolf A, Evers Silvia M A A, Hiligsmann Mickaël, Michels Michelle

Abstract excerpt

INTRODUCTION: Hypertrophic cardiomyopathy (HCM) is the most prevalent inherited cardiac disease. The impact of HCM on quality of life (QoL) and societal costs remains poorly understood. This prospective multi-centre burden of disease study estimated QoL and societal costs of genotyped HCM patients and genotype-positive phenotype-negative (G+/P-) subjects. METHODS AND RESULTS: Participants were categorized into...

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Identifiers

PMID: 39520534
DOI: 10.1093/ehjqcco/qcae092
PMCID: PMC11879321

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