Spermatogenic failure in male mice lacking H-Y antigen.

doi:10.1038/320170a0

Back to search

Article

Spermatogenic failure in male mice lacking H-Y antigen.

Nature - 1 Jan 2000

Burgoyne P S, Levy E R, McLaren A

Abstract excerpt

The mammalian Y chromosome carries a factor that initiates male sexual development by directing the fetal gonads to form testes. Wachtel and his colleagues proposed that this testis-determining function of the Y is mediated by the male-specific cell-surface antigen H-Y, originally defined by skin...

Topics

Animals
Copulation
H-Y Antigen
Infertility, Male
Male
Meiosis
Mice
Mutation
Sexual Behavior, Animal
Spermatogenesis
Testis

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.