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Article

A Novel Delivery Approach of Clinical Inner Ear Gene Therapy

6 Nov 2024

Abstract excerpt

BACKGROUND: To create and develop a delivery approach for clinical inner ear gene therapy, we conducted a study of trans-round window membrane (RWM) microinjection using a pipetting microneedle via transcanal endoscopic ear surgery (TEES). METHODS: The implementation of the trans-RWM microinjection surgery involved seven cadaveric specimens, and the surgical procedures and the pipetting microneedle were developed...

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Share to Ear Surgery and Otitis Media
Share to Hearing, Cochlea, Tinnitus, Genetics
Share to Vestibular and auditory disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39511736
DOI: 10.1097/mao.0000000000004366

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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