The Val66Met variant of brain-derived neurotrophic factor is linked to reduced telomere length in a military population: a pilot study.

doi:10.1038/s41598-024-78033-x

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The Val66Met variant of brain-derived neurotrophic factor is linked to reduced telomere length in a military population: a pilot study.

Scientific reports - 6 Nov 2024

Allsopp Richard C, Hernández Lisa M, Taylor Marcus K

Abstract excerpt

In military populations, gene-environment interactions can influence performance and health outcomes. Brain-derived neurotrophic factor (BDNF) is a central nervous system protein that is important for neuronal function and synaptic plasticity. A BDNF single nucleotide polymorphism, rs6265, leads to an amino acid substitution of valine (Val) with methionine (Met) at codon 66 (Val66Met), which may influence an...

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PMID: 39506036
DOI: 10.1038/s41598-024-78033-x
PMCID: PMC11542005

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