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Article

ELF1 serves as a potential biomarker for the disease activity and renal involvement in systemic lupus erythematosus.

Scientific reports - 4 Nov 2024

Zhang Yukun, Cai Minglong, Huang Xiaoyi, Zhang Li, Wen Leilei, Zhu Zhengwei, Gao Jinping, Sheng Yujun

Abstract excerpt

Systemic lupus erythematosus (SLE) is an autoimmune disease that affects multiple organs, yet its underlying mechanisms remain unclear, and precise biomarkers are lacking. In this study, we employed Mendelian randomization and HEIDI tools to comprehensively analyze large-scale Genome-Wide Association Study (GWAS) and expression Quantitative Trait Loci (eQTL) data, leading to the identification of seven novel...

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Identifiers

PMID: 39496744
DOI: 10.1038/s41598-024-78593-y
PMCID: PMC11535329

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