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VISTA-mediated immune evasion in cancer

31 Oct 2024

Abstract excerpt

Over the past decade, V-domain immunoglobulin suppressor of T-cell activation (VISTA) has been established as a negative immune checkpoint molecule. Since the role of VISTA in inhibiting T-cell activation was described, studies have demonstrated other diverse regulatory functions in multiple immune cell populations. Furthermore, its relevance has been identified in human cancers. The role of VISTA in cancer...

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PMID: 39482534
DOI: 10.1038/s12276-024-01336-6

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