Article
Association Between Gross Features and Coexistence of BRAFV600E and TERT Promoter Mutations in Papillary Thyroid Carcinomas: A Combined Analysis Incorporating Clinicopathologic Features.
Thyroid : official journal of the American Thyroid Association - 1 Dec 2024
Nguyen Thi Ngoc Anh, Nguyen Van Phu Thang, Kurohama Hirokazu, Akazawa Yuko, Matsuda Katsuya, Mussazhanova Zhanna, Matsuoka Yuki, Yokota Kenichi, Satoh Shinya, Yamashita Hiroyuki, Nguyen Thi Nhung, Sailaubekova Yerkerzhan, Nakashima Masahiro
Abstract excerpt
Background: The coexistence of v-Raf murine sarcoma viral oncogene homolog B1 (BRAFV600E) and telomere reverse transcriptase promoter (TERT-p) mutations is considerably associated with aggressiveness and poor prognosis in papillary thyroid carcinoma (PTC). However, the association between gross findings and genetic alterations in PTC remains unknown. We aimed to investigate the association between...
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