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Article

Effects of Coexistent BRAFV600E and TERT Promoter Mutations on Poor Clinical Outcomes in Papillary Thyroid Cancer: A Meta-Analysis.

Thyroid : official journal of the American Thyroid Association - 1 May 2017

Moon Shinje, Song Young Shin, Kim Ye An, Lim Jung Ah, Cho Sun Wook, Moon Jae Hoon, Hahn Seokyung, Park Do Joon, Park Young Joo

Abstract excerpt

BACKGROUND: The presence of a telomerase reverse transcriptase (TERT) promoter mutation has been suggested as a potential prognostic marker for thyroid cancer, and a synergistic association with the BRAFV600E mutation has been demonstrated. The aim of this study was to verify the role of this genetic duet in papillary thyroid cancer (PTC). METHODS: Studies of the association of BRAFV600E and TERT promoter...

Read the complete abstract on PubMed

Topics

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Share to Carcinoma, Papillary
Share to TERT gene

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mutation

Share to Prognosis

Share to Promoter Regions, Genetic

Share to Proto-Oncogene Proteins B-raf

Share to Telomerase

Share to Thyroid Neoplasms

Source

Identifiers

PMID: 28181854
DOI: 10.1089/thy.2016.0350

Genes

TERT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Effects of Coexistent BRAFV600E and TERT Promoter Mutations on Poor Clinical Outcomes in Papillary Thyroid Cancer: A Meta-Analysis.PMID 28181854Read ↗

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