Article
The Animal Variant Classification Guidelines v2: An Update With New Criteria and Improved Clarifications.
Animal genetics - 1 Oct 2026
Desmet Lore, Ferrari Carlotta, Abitbol Marie, Anderson Heidi, Bannasch Danika, Bauer Hubert, Bell Jerold, Bilgen Nüket, Chevallier Lucie, Dufaure de Citres Caroline, Donner Jonas, Finno Carrie J, Giovambattista Guillermo, Harrison Steven M, Hayward Jessica J, Häggström Jens, Huff Jason T, Leeb Tosso, Ljungvall Ingrid, Longeri Maria, Lyons Leslie A, Martinez Marcela, Mellersh Cathryn, Nicholas Frank W, Ohlsson Åsa, Petersen Jessica L, Smets Pascale, Strillacci Maria G, Tammen Imke, Van Buren Samantha, van Steenbeek Frank G, Broeckx Bart J G
Abstract excerpt
The Animal Variant Classification Guidelines (AVCG) were developed to standardize and objectify the classification of putative disease-causing variants. These guidelines are sufficiently reproducible and are used to classify previously published and new disease-causing variants across species. Here, the guidelines are updated (AVCG.v2), based on a three-phase decision process. Overall, four new criteria and seven...
Read the complete abstract on PubMedTopics
- Animals
- Genetic Variation
- Genetic Testing