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Article

stSNV: a comprehensive resource of SNVs in spatial transcriptome.

Nucleic acids research - 6 Jan 2025

Yang Changbo, Liu Yujie, Wang Xiaohua, Jia Qing, Fan Yuqi, Lu Zhenglin, Shi Jingyi, Liu Zhaoxin, Chen Gengdong, Li Jianing, Lu Weijian, Zhou Weiwei, Lv Dezhong, Zou Haozhe, Xu Juan, Li Yongsheng, Jiang Qinghua, Wang Tao, Shao Tingting

Abstract excerpt

Single nucleotide variants (SNVs), as important components of genetic variation, affect gene expression, function and phenotype. Mining and summarizing the spatial distribution of SNVs in diseased and normal tissues for a better understanding of their characteristics and potential roles in cell-lineage determination, aging, or disease occurrence is significant. Herein, we have developed a comprehensive spatial...

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PMID: 39470702
DOI: 10.1093/nar/gkae945
PMCID: PMC11701523

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