Article
Esophageal cancer risk is influenced by genetically determined blood metabolites.
Medicine - 25 Oct 2024
Deng Jieyin, Wu Silin, Huang Ye, Deng Yi, Yu Ke
Abstract excerpt
It remains unclear what causes esophageal cancer (EC), but blood metabolites have been connected to it. Our study performed a Mendelian randomization (MR) analysis to assess the causality from genetically proxied 1400 blood metabolites to EC level. A two-sample MR analysis was employed to evaluate the causal relationship between 1400 blood metabolites and EC. Initially, the EC genome-wide association study (GWAS)...
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