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Article

Human blood metabolites and gastric cancer: a Mendelian randomization analysis.

BMC gastroenterology - 30 Dec 2024

Zhang Chao, Huang Dao Lai, Zhou Kun, Cai Jin Tao, Liu Dang, Tan Ming Hao, Zhu Guan Yu, Wu Xiang Hua

Abstract excerpt

BACKGROUND: Gastric cancer (GC) remains one of the predominant malignant tumors within the digestive tract, yet its underlying biological mechanisms remain elusive. The primary objective of this study is to delineate the causal relationship between circulating metabolites and GC. METHOD: The primary Mendelian randomization (MR) analysis was based on three large GWAS datasets. While the inverse variance weighted...

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Identifiers

PMID: 39736510
DOI: 10.1186/s12876-024-03576-2
PMCID: PMC11684236

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