Article
Skin metastasis of BRCA mutated prostate cancer: A case report and a brief review of literature.
Medicine - 11 Oct 2024
Jubran Salim, Basso Umberto, Milani Anna, Erbetta Elisa, Di Marco Andrea, Pittarello Chiara, Cavasin Nicolò, Lai Eleonora, Stragliotto Silvia, Pierantoni Francesco, Zampiva Ilaria, Bimbatti Davide, Maruzzo Marco
Abstract excerpt
RATIONALE: Metastatic castration-resistant prostate cancer has a poor prognosis especially when harboring DNA damage repair gene mutations, nevertheless, in the case of pathogenic BRCA gene mutations, PARPi demonstrated a survival benefit and is a validated treatment. Nowadays, there is no data regarding unusual metastases after these drugs. Cutaneous metastases appear rarely in prostate cancer and were...
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