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Article

Risk of celiac disease autoimmunity is modified by interactions between CD247 and environmental exposures.

Scientific reports - 26 Oct 2024

Eurén Anna, Lynch Kristian, Lindfors Katri, Parikh Hemang, Koletzko Sibylle, Liu Edwin, Akolkar Beena, Hagopian William, Krischer Jeffrey, Rewers Marian, Toppari Jorma, Ziegler Anette, Agardh Daniel, Kurppa Kalle

Abstract excerpt

Season of birth, viral infections, HLA haplogenotypes and non-HLA variants are implicated in the development of celiac disease and celiac disease autoimmunity, suggesting a combined role of genes and environmental exposures. The aim of the study was to further decipher the biological pathways conveying the season of birth effect in celiac disease autoimmunity to gain novel insights into the early pathogenesis of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39462122
DOI: 10.1038/s41598-024-75496-w
PMCID: PMC11567144

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