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Cell Migration–Proliferation Dichotomy in Cancer: Biological Fact or Experimental Artefact?

24 Sept 2024

Abstract excerpt

The migration-proliferation dichotomy (MPD) has long been observed in cultured cancer cells. This phenomenon is not only relevant to tumour progression but may also have therapeutic significance in clinical cancer. However, MPD has rarely been investigated in primary cancer. This study aimed to either confirm or disprove the existence of MPD in primary cancer. Using primary gastric, colorectal and prostate cancer...

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PMID: 39452063
DOI: 10.3390/biology13100753

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