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Article

Circulating ketone bodies, genetic susceptibility, with left atrial remodeling and atrial fibrillation: A prospective study from the UK Biobank.

Heart rhythm - 1 Sept 2025

Zhang Nan, Liu Daiqi, Zhao Jinhua, Tse Gary, Zhou Jiandong, Zhang Qingpeng, Lip Gregory Y H, Liu Tong

Abstract excerpt

BACKGROUND: Ketone bodies (KBs) are an important cardiac metabolic energy source. Metabolic remodeling has recently been found to play an important role in the pathological process of atrial fibrillation (AF). OBJECTIVE: The purpose of this study was to evaluate the associations of circulating KB levels with incident AF risk in the general population. METHODS: We studied 237,163 participants [mean age, 56.5...

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PMID: 39433077
DOI: 10.1016/j.hrthm.2024.10.028

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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