Article
NKT cells - New players in CAR cell immunotherapy?
European journal of haematology - 1 Dec 2018
Kriegsmann Katharina, Kriegsmann Mark, von Bergwelt-Baildon Michael, Cremer Martin, Witzens-Harig Mathias
Abstract excerpt
Low levels of peripheral blood natural killer T (NKT) cells in cancer patients and a favorable outcome associated with a high number of tumor-infiltrating NKT cells demonstrated in several studies indicated the important role of these immune cells in the antitumor response. With effective antitumor immunity via direct tumor lysis, cytokine modulation of effector cells and regulation of immunosuppressive cells,...
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