Article
A new face in the treatment of Philadelphia chromosome-positive acute lymphoblastic leukaemia.
British journal of haematology - 1 Dec 2024
Kondo Takeshi
Abstract excerpt
The prognosis for patients with relapsed/refractory or measurable (minimal) residual disease-positive Philadelphia chromosome (Ph)-positive acute lymphoblastic leukaemia (ALL) is poor. Currently, ponatinib is the only approved tyrosine kinase inhibitor (TKI) that is effective for Ph-positive ALL with the T315I mutation. Although the report by Liu et al. is a retrospective observational study, it offers prospects...
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