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Epidemic of multiple Treponema pallidum strains in men who have sex with men in Japan: efficient multi-locus sequence typing scheme and indicator biomarkers.

AIDS research and therapy - 16 Oct 2024

Sato Wakana, Sedohara Ayako, Koga Michiko, Nakagama Yu, Yotsuyanagi Hiroshi, Kido Yasutoshi, Adachi Eisuke

Abstract excerpt

BACKGROUND: The challenges in culturing Treponema pallidum have hindered molecular-biological analysis. This study aims to establish a molecular epidemiological analysis of syphilis among Japanese men who have sex with men (MSM) and to investigate the relationship between bacteremia and associated pathophysiology. METHODS: We used whole blood specimens from syphilis-diagnosed individuals in Tokyo, collected...

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PMID: 39415268
DOI: 10.1186/s12981-024-00663-y
PMCID: PMC11484458

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