Article
Coadaptation of Helicobacter pylori and humans: ancient history, modern implications.
The Journal of clinical investigation - 1 Sept 2009
Atherton John C, Blaser Martin J
Abstract excerpt
Humans have been colonized by Helicobacter pylori for at least 50,000 years and probably throughout their evolution. H. pylori has adapted to humans, colonizing children and persisting throughout life. Most strains possess factors that subtly modulate the host environment, increasing the risk of peptic ulceration, gastric adenocarcinoma, and possibly other diseases. H. pylori genes encoding these and other...
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