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Article

Mechanism of Drug Resistance to First-Line Chemotherapeutics Mediated by TXNDC17 in Neuroblastomas.

Cancer reports (Hoboken, N.J.) - 1 Oct 2024

Zeng Chenggong, Li Zhuoran, Wei Zhiqing, Chen Tingting, Wang Juan, Huang Junting, Sun Feifei, Zhu Jia, Lu Suying, Zhen Zijun

Abstract excerpt

BACKGROUND: The prognosis of high-risk neuroblastomas (NB) that are resistant to first-line induction chemotherapy is relatively poor. This study explored the mechanism of resistance to first-line chemotherapeutics mediated by TXNDC17 and its potential solutions in NB. METHODS: The genetic and clinical data of patients with NB were obtained from the Therapeutically Applicable Research to Generate Effective...

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Source

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Identifiers

PMID: 39411839
DOI: 10.1002/cnr2.70033
PMCID: PMC11480999

Genes

TXNDC17
BECN1
EFS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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