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Article

The FoxM1-ABCC4 axis mediates carboplatin resistance in human retinoblastoma Y-79 cells

26 Jun 2018

Abstract excerpt

Carboplatin is the most commonly used drug in the first-line treatment of human retinoblastoma (RB), but its clinical application is greatly limited due to acquired drug resistance upon the long-term treatment. Forkhead box protein M1 (FoxM1) is the transcription factor aberrantly expressed in various types of human cancers, which plays an essential role in the regulation of tumorigenesis, tumor metastasis and...

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PMID: 30060118
DOI: 10.1093/abbs/gmy080

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