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Associations between methamphetamine use disorder and SLC18A1, SLC18A2, BDNF, and FAAH gene sequence variants and expression levels.

Dialogues in clinical neuroscience - 1 Jan 2024

Guerin Alexandre A, Spolding Briana, Bozaoglu Kiymet, Swinton Courtney, Liu Zoe, Panizzutti Parry Bruna, Truong Trang, Dean Brian, Lawrence Andrew J, Bonomo Yvonne, Nestler Eric J, Hamilton Peter J, Berk Michael, Rossell Susan, Walder Ken, Kim Jee Hyun

Abstract excerpt

INTRODUCTION: Assessing candidate gene sequence variations and expression helps to understand methamphetamine use disorder and inform potential treatments. We investigated single nucleotide polymorphisms (SNPs) and gene expression in four candidate genes: SLC18A1, SLC18A2, BDNF, and FAAH, between controls and people with methamphetamine use disorder. METHODS: Fifty-nine participants (29 people with...

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Identifiers

PMID: 39394974
DOI: 10.1080/19585969.2024.2413476
PMCID: PMC11486062

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