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Article

Phenotypically plastic drug-resistant chronic myeloid leukaemia cell line displays enhanced cellular dynamics in a zebrafish xenograft model.

Journal of cellular and molecular medicine - 1 Oct 2024

Baykal Seda, Yuce Zeynep, Ozhan Gunes

Abstract excerpt

Understanding the mechanisms by which cancer cells switch between different adaptive states and evade therapeutic interventions is essential for clinical management. In this study, the in vivo cellular dynamics of a new chronic myeloid leukaemia cell line displaying altered phenotype and resistance to tyrosine kinase inhibitors were investigated in correlation with their parental cells for...

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Share to Drug Resistance, Neoplasm

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Imatinib Mesylate

Share to Leukemia, Myelogenous, Chronic, BCR-ABL Positive

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Share to Neovascularization, Pathologic

Share to Xenograft Model Antitumor Assays

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Identifiers

PMID: 39392217
DOI: 10.1111/jcmm.70105
PMCID: PMC11467800

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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