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Article

Effects of immunorelated gene polymorphisms on trastuzumab targeting breast cancer cell in vitro.

Pharmacogenomics - 1 Jan 2024

Yu Linyu, Zhang Congmin, Liu Liangyu, Chen Xiaoping

Abstract excerpt

Aim: To investigate the associations between genetic polymorphisms in immunorelated genes and PBMC-induced cytotoxicity to breast cancer cell with the treatment of trastuzumab in vitro.Methods: Trastuzumab-mediated cytotoxicity of peripheral blood mononuclear cells (PBMC) from 148 healthy donors and 13 BC patients was analyzed by flow cytometry. 16 SNPs in 7 immunorelated genes were genotyped by Sequenom Mass...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39392082
DOI: 10.1080/14622416.2024.2404819
PMCID: PMC11492633

Genes

CD247

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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